COMPLEXES OF AZITHROMYCIN WITH SOME DIVALENT METAL-IONS

被引：0
作者：
DOKIC, S
VAJTNER, Z
LOPOTAR, N
MRVOSSERMEK, D
KAMENAR, B
NAGL, A
机构：
[1] UNIV ZAGREB,FAC SCI,GEN & INORGAN CHEM LAB,ZAGREB 41000,CROATIA
[2] UNIV ZAGREB,FAC TECHNOL,INST TEXT & CLOTHING,ZAGREB 41000,CROATIA
来源：
CROATICA CHEMICA ACTA | 1995年 / 68卷 / 02期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The formation of 2 : 1 complexes of azithromycin with copper(II), zinc(II), cobalt(II), nickel(II), magnesium(II) and calcium(II) ions was examined. These compounds (2-7) showed the same in vitro biological potency as azithromycin (1). The complexes (3-7) are isostructural and different when compared with azithromycin-Cu(II)- complex. Copper(II)-complex (2) was most stable and selected for structure determination by X-ray crystallography. Some physical characteristics and analyses of the complexes are also presented.
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页码：375 / 381
页数：7
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