AMITRIPTYLINE PRODUCES ANALGESIA IN THE FORMALIN PAIN TEST

被引：47

作者：

ACTON, J

MCKENNA, JE

MELZACK, R

机构：

[1] Department of Psychology, McGill University, Montreal, Que. H3A 1B1

来源：

EXPERIMENTAL NEUROLOGY | 1992年 / 117卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/0014-4886(92)90116-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A dose of 20 mg/kg of amitriptyline reduced pain in the second phase of the formalin test, which is an animal model of long-lasting pain in humans. Since the analgesic effect was produced by a single dose, which is insufficient to produce an antidepressant effect, these results indicate that amitriptyline has analgesic properties that are independent of its antidepressant properties. © 1992.

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页码：94 / 96

页数：3

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