EUONYMOSIDE-A - A NEW CYTOTOXIC CARDENOLIDE GLYCOSIDE FROM THE BARK OF EUONYMUS-SIEBOLDIANUS

被引：18
作者：
BAEK, NI
LEE, YH
PARK, JD
KIM, SI
AHN, BZ
机构：
[1] KOREA GINSENG & TOBACCO RES INST,NAT PROD LAB,TAEJON 305345,SOUTH KOREA
[2] CHUNGNAM NATL UNIV,COLL PHARM,TAEJON 305764,SOUTH KOREA
来源：
PLANTA MEDICA | 1994年 / 60卷 / 01期
关键词：
EUONYMUS SIEBOLDIANUS; CELASTRACEAE; CARDENOLIDE; EUONYMOSIDE A; CYTOTOXICITY;
D O I：
10.1055/s-2006-959401
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new cytotoxic cardenolide glycoside, euonymoside A (1), was isolated from the bark of Euonymus sieboldianus. The structure of 1 was elucidated as acovenosigenin A-3-0-beta-D-glucopyranosyl (1-->2)-alpha-L-rhamnopyranoside. The IC50 values of 1 against A549 (human lung carcinoma) and SK-OV-3 (human ovary adenocarcinoma) were 0.06 and 0.4 mu g/ml, respectively.
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页码：26 / 29
页数：4
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