CONFIRMATION OF ANTI-HCV EIA REACTIVITIES BY RIBA AND NEUTRALIZATION ASSAY AMONG BLOOD-DONORS AND PATIENTS WITH CHRONIC LIVER-DISEASE AND HEPATOCELLULAR-CARCINOMA

被引：0

作者：

TANZI, E

GALLI, C

DELAITO, M

BERTIN, T

PIZZOCOLO, G

RODELLA, A

BUSCARINI, L

SBOLLI, G

ROSSI, U

ROMANO, L

CHIARAMONTE, M

ZANETTI, AR

机构：

[1] UNIV CAMERINO,DEPT HYG,VIALE E BETTI 3,I-62032 CAMERINO,ITALY

[2] INST VIROL,INST VIROL,GLASGOW G11 5JR,SCOTLAND

[3] UNIV PADUA,DEPT GASTROENTEROL,I-35100 PADUA,ITALY

[4] HOSP BRESCIA,BRESCIA,ITALY

[5] HOSP PIACENZA,PIACENZA,ITALY

[6] HOSP LEGANO,LEGANO,ITALY

来源：

ARCHIVES OF VIROLOGY | 1992年

关键词：

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The aim of our study was to confirm by Recombinant Immunoblot Assay (RIBA) and by neutralization assay the repeat positive reactions found by two commercially available EIAs (Ortho and Abbott) when testing samples from volunteer blood donors, patients with chronic liver disease and with hepatocellular carcinoma. Our data show a high confirmatory rate among patients with chronic viral NANBH and HCC, while among donors and patients with CLD other than NANBH the percentage of presumptive EIA positive reactions confirmed by RIBA and/or neutralization assay is much lower. In our experience, the neutralization assay appears to be somewhat more sensitive than RIBA, especially when samples show low EIA optical densities.

引用

页码：227 / 231

页数：5

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