EFFECT OF PREGNANCY ON DEVELOPMENT OF GALACTOSE-INDUCED CATARACT IN RAT

被引：0

作者：

TESHIMA, R ^{[1
]}

TAURA, T ^{[1
]}

OKAMURA, R ^{[1
]}

机构：

[1] KUMAMOTO ROSAI HOSP,DEPT OPHTHALMOL,KUMAMOTO,JAPAN

来源：

JAPANESE JOURNAL OF OPHTHALMOLOGY | 1993年 / 37卷 / 01期

关键词：

BLOOD GALACTOSE; GALACTOSE CATARACT; LENS GALACTITOL; PREGNANCY;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The effect of pregnancy on the development of galactose-induced cataract was studied in rats. Eight-week-old rats were fed a 50% galactose diet for 4 weeks. The rats were divided into three groups: nonpregnant females, pregnant females, and males. All eyes were examined by slit-lamp biomicroscope at 11 and 12 weeks of age, and the lenses were morphologically examined at 12 weeks. Clinically, the cataract showed a less advanced stage in the eyes of pregnant rats than in the eyes of the other two groups. Morphologically, the lenses of pregnant rats retained their normal structure. However, the lenses of the other two groups showed extensive damage. The plasma galactose levels and galactitol levels in lenses showed no significant difference among the three groups. Pregnancy was proved to inhibit the development of galactose cataract.

引用

页码：56 / 61

页数：6

共 10 条

[1]

Akada S, 1991, Nihon Sanka Fujinka Gakkai Zasshi, V43, P523

[2]

DENISOV YP, 1978, FARMAKOL TOKSIKOL, V41, P697

[3]

KANEDA M, 1991, ATARASHII GANKA, V8, P93

[4]

KAYA H, 1983, IGAKU NO AYUMI, V131, P361

[5]

KINOSHITA JIN H., 1965, INVEST OPHTHALMOL, V4, P786

[6] BIOCHEMICAL CHANGES ASSOCIATED WITH DEVELOPMENT AND REVERSAL OF GALACTOSE CATARACTS [J].

REDDY, VN ;

SCHWASS, D ;

CHAKRAPANI, B ;

LIM, CP .

EXPERIMENTAL EYE RESEARCH, 1976, 23 (05) :483-493

[7]

ROMMEL K, 1968, KLIN WOCHENSCHR, V46, P963

[8] EFFECT OF SODIUM IODATE INJECTION ON THE DEVELOPMENT OF GALACTOSE CATARACT IN THE RAT [J].

TAURA, T ;

REDDY, VN .

OPHTHALMIC RESEARCH, 1988, 20 (05) :286-292

[9]

TESHIMA R, 1991, JPN J OPHTHALMOL, V35, P317

[10]

WORLEY RJ, 1990, GYNECOL OBSTET, V5, P1

← 1 →