A STEREOSPECIFIC SYNTHESIS OF (-)-BESTATIN FROM L-MALIC ACID

被引：57

作者：

NORMAN, BH

MORRIS, ML

机构：

[1] Monsanto Corporate Research, Chemical Sciences, St. Louis, MO 63167

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(00)61780-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly diastereospecific route to (-)-Bestatin from L-Malic Acid has been developed. This approach features a stereocontrolled alkylation of diethyl (S)-malate and proceeds through an oxazolidone via a Curtius Rearrangement.

引用

页码：6803 / 6806

页数：4

共 22 条

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