FLAVONE FORMATION IN THE WHEELER AURONE SYNTHESIS

被引：11

作者：

DONNELLY, JA

HIGGINBOTHAM, CL

机构：

来源：

TETRAHEDRON | 1990年 / 46卷 / 20期

关键词：

D O I：

10.1016/S0040-4020(01)87902-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dihydrochalcones formed by bromomethylation of the side-chain of 2'-acetoxychalcones were found to produce minor quantities of flavones as well as the major product aurones when cyclized by aqueous ethanolic sodium hydroxide. The yields of flavone increased with increasing base concentration. The optimum concentration of hydroxide for aurone formation was below 1%. Greatly diminished yields of O-heterocycles were obtained when a nitro substituent was introduced para to the cyclizing 2'-oxy function. © 1990.

引用

页码：7219 / 7226

页数：8

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