THE HUMAN MDR3-GENE ENCODES A NOVEL P-GLYCOPROTEIN HOMOLOG AND GIVES RISE TO ALTERNATIVELY SPLICED MESSENGER-RNAS IN LIVER

被引：273
作者：
VANDERBLIEK, AM
BAAS, F
DELANGE, TT
KOOIMAN, PM
VANDERVELDEKOERTS, T
BORST, P
机构：
来源：
EMBO JOURNAL | 1987年 / 6卷 / 11期
关键词：
D O I：
10.1002/j.1460-2075.1987.tb02653.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：3325 / 3331
页数：7
相关论文
共 44 条
[1]   HOMOGENEOUSLY STAINING CHROMOSOMAL REGIONS CONTAIN AMPLIFIED COPIES OF AN ABUNDANTLY EXPRESSED CELLULAR ONCOGENE (C-MYC) IN MALIGNANT NEUROENDOCRINE CELLS FROM A HUMAN-COLON CARCINOMA [J].
ALITALO, K ;
SCHWAB, M ;
LIN, CC ;
VARMUS, HE ;
BISHOP, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (06) :1707-1711
[2]   THE BASIS OF MULTIDRUG RESISTANCE IN MAMMALIAN-CELLS - HOMOLOGY WITH BACTERIAL TRANSPORT [J].
AMES, GF .
CELL, 1986, 47 (03) :323-324
[3]  
AUFFRAY C, 1980, EUR J BIOCHEM, V107, P303
[4]   INTERNAL DUPLICATION AND HOMOLOGY WITH BACTERIAL TRANSPORT PROTEINS IN THE MDR1 (P-GLYCOPROTEIN) GENE FROM MULTIDRUG-RESISTANT HUMAN-CELLS [J].
CHEN, CJ ;
CHIN, JE ;
UEDA, K ;
CLARK, DP ;
PASTAN, I ;
GOTTESMAN, MM ;
RONINSON, IB .
CELL, 1986, 47 (03) :381-389
[5]   MEMBRANE-VESICLES FROM MULTIDRUG-RESISTANT HUMAN CANCER-CELLS CONTAIN A SPECIFIC 150-KDA TO 170-KDA PROTEIN DETECTED BY PHOTOAFFINITY-LABELING [J].
CORNWELL, MM ;
SAFA, AR ;
FELSTED, RL ;
GOTTESMAN, MM ;
PASTAN, I .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (11) :3847-3850
[6]  
CORNWELL MM, 1987, J BIOL CHEM, V262, P2166
[7]   SIMILAR BIOCHEMICAL-CHANGES ASSOCIATED WITH MULTIDRUG RESISTANCE IN HUMAN-BREAST CANCER-CELLS AND CARCINOGEN-INDUCED RESISTANCE TO XENOBIOTICS IN RATS [J].
COWAN, KH ;
BATIST, G ;
TULPULE, A ;
SINHA, BK ;
MYERS, CE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (24) :9328-9332
[8]   ACTIVE OUTWARD TRANSPORT OF DAUNOMYCIN IN RESISTANT EHRLICH ASCITES TUMOR-CELLS [J].
DANO, K .
BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 323 (03) :466-483
[9]   DIFFERENTIAL AMPLIFICATION AND DISPROPORTIONATE EXPRESSION OF 5 GENES IN 3 MULTIDRUG-RESISTANT CHINESE-HAMSTER LUNG CELL-LINES [J].
DEBRUIJN, MHL ;
VANDERBLIEK, AM ;
BIEDLER, JL ;
BORST, P .
MOLECULAR AND CELLULAR BIOLOGY, 1986, 6 (12) :4717-4722
[10]   PEMBL - A NEW FAMILY OF SINGLE STRANDED PLASMIDS [J].
DENTE, L ;
CESARENI, G ;
CORTESE, R .
NUCLEIC ACIDS RESEARCH, 1983, 11 (06) :1645-1655
12345