GENES, TREES AND INFECTIONS - MOLECULAR EVIDENCE IN EPIDEMIOLOGY

被引：13

作者：

HOLMES, EC

GARNETT, GP

机构：

[1] Dept of Zoology, University of Oxford, Oxford, UK 0X1 3PS, South Parks Road

来源：

TRENDS IN ECOLOGY & EVOLUTION | 1994年 / 9卷 / 07期

关键词：

D O I：

10.1016/0169-5347(94)90291-7

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

Molecular phylogenies constitute an important new way of tracking the prepress of viral epidemics. The phylogenetic analysis of viral sequence data provides information on the origin, spread and maintenance of infections and can be used to reconstruct contact networks of infected individuals. Analysis of the branching structure of phylogenetic trees also allows inferences to be made about the rate of transmission and the distinction between endemic and epidemic infections, and provides estimates of the numbers of infected individuals.

引用

页码：256 / 260

页数：5

共 33 条

[1]

ANDERSON R M, 1991

[2]

Bernard H U, 1994, Curr Top Microbiol Immunol, V186, P33

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