A SOLUBLE FORM OF GUANYLATE-CYCLASE IN THE MOLECULAR MECHANISM OF THE PHYSIOLOGICAL-EFFECTS OF NITROGEN-OXIDE AND IN THE REGULATION OF PLATELET-AGGREGATION

被引：0

作者：

SEVERINA, IS ^{[1
]}

机构：

[1] RUSSIAN ACAD MED SCI, INST BIOMED CHEM, DEPT PHYSIOL ACT PEPTIDES & GUANYLATE CYCLASE SYS, MOSCOW 119832, RUSSIA

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1995年 / 119卷 / 03期

关键词：

GUANYLATE CYCLASE; HEME; NITROGEN OXIDE; HUMAN PLATELETS; AGGREGATION;

D O I：

10.1007/BF02445819

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The article is devoted to the role of heme in soluble guanylate cyclase functioning, the molecular mechanism of nitrogen oxide activation of guanylate cyclase, the role of guanylate cyclase in the process of platelet aggregation, and the mechanism of the antihypertensive and antiaggregative action of certain activators of the enzyme.

引用

页码：219 / 224

页数：6

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