CONCEPT OF INTERNAL STRUCTURAL CONTROLS FOR EVALUATION OF INACTIVE SYNTHETIC PEPTIDE ANALOGS - SYNTHESIS OF [ORN13,14]APAMIN AND ITS GUANIDINATION TO A APAMIN DERIVATIVE WITH FULL NEUROTOXIC ACTIVITY

被引：57

作者：

COSAND, WL ^{[1
]}

MERRIFIELD, RB ^{[1
]}

机构：

[1] ROCKEFELLER UNIV,NEW YORK,NY 10021

来源：

关键词：

D O I：

10.1073/pnas.74.7.2771

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：2771 / 2775

页数：5

共 37 条

[1] THE SYNTHESIS OF PEPTIDE DERIVATIVES OF BASIC AMINO-ACIDS
BARRASS, BC
ELMORE, DT
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1957, (JUL): : 3134 - 3139
[2] SYNTHESIS OF ARGINE-CONTAINING PEPTIDES THROUGH THEIR ORNITHINE ANALOGS . SYNTHESIS OF ARGININE VASOPRESSIN ARGININE VASOTOCIN + L-HISTIDYL-L-PHENYLALANYL-L-ARGINYL-L-TRYPTOPHYLGLYCINE
BODANSZKY, M
ONDETTI, MA
THOMAS, PL
BIRKHIMER, CA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (20) : 4452 - &
[3] BIOLOGICALLY ACTIVE CITRULLINE PEPTIDES
BODANSZKY, M
PIALA, JJ
FRIED, J
ANGELOND.M
BIRKHIMER, CA
SHEEHAN, JT
RUBIN, B
[J]. NATURE, 1962, 194 (4827) : 485 - &
[4] BORIN G, 1972, INT J PROT RES, V4, P37
[5] BUIS J, 1973, THESIS CATHOLIC U, P127
[6] CALLEWAERT G L, 1968, Febs Letters, V1, P111, DOI 10.1016/0014-5793(68)80033-X
[7] ACTIVE DERIVATIVES OF A POLYPEPTIDE INHIBITOR OF TRYPSIN (KUNITZ AND NORTHROP INHIBITOR)
CHAUVET, J
ARCHER, R
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1967, 27 (02) : 230 - &
[8] CHERVENKA CH, 1956, J BIOL CHEM, V222, P635
[9] ERICKSON BW, 1974, ISRAEL J CHEM, V12, P79
[10] ERICKSON BW, 1976, PROTEINS, V2, P257