SYMPTOMS OF PANCREATIC-CANCER

被引：102

作者：

KRECH, RL

WALSH, D

机构：

[1] Palliative Care Service, Cleveland Clinic Cancer Center, Cleveland, OH

[2] Department of Hematology/Oncology, Cleveland Clinic Cancer Center, Cleveland, OH

来源：

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 1991年 / 6卷 / 06期

关键词：

ADVANCED CANCER; SYMPTOMS; PANCREAS;

D O I：

10.1016/0885-3924(91)90027-2

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

We describe the symptoms, physical findings, treatment interventions, risk factors, and length of survival in persons with pancreatic cancer referred to a palliative care service (PCS) in a tertiary care facility. Data were collected prospectively over a 2-yr period using a standard clinical assessment tool in 39 patients with unresectable pancreatic cancer. Common symptoms include pain (82%), anorexia (64%), early satiety (62%), xerostomia and sleep problems (both 54%), and weight loss (51%). Analyzed retrospectively, 82% had at least one known risk factor for the development of pancreatic cancer. Twenty-five people presented to the PCS within 1 mo of diagnosis; in this group, length of survival was analyzed according to the presence of specific symptoms, and a significant inverse relationship between the presence of dyspnea and length of survival was found. As there is no effective treatment for surgically unresectable pancreatic cancer, palliation of common symptoms should be the primary emphasis of therapy.

引用

页码：360 / 367

页数：8

共 14 条

[1]

Silverberg, Boing, Squires, Cancer statistics 1990, CA: A Cancer Journal for Clinicians, 40, pp. 9-26, (1990)

[2]

Gudjonsson, Cancer of the pancreas: Fifty years of surgery, Cancer, 60, pp. 2284-2303, (1987)

[3]

Fontham, Correa, Epidemiology of pancreatic cancer, Surg Clin North Am, 69, pp. 551-567, (1989)

[4]

Hermann, Copperman, Current concepts in cancer, N Engl J Med, 301, pp. 482-485, (1979)

[5]

Warshaw, Swanson, Pancreatic cancer in 1988: Possibilities and probabilities, Ann Surg, 208, pp. 541-553, (1988)

[6]

Jordan, Pancreatic resection for pancreatic cancer, Surg Clin North Am, 69, pp. 569-597, (1989)

[7]

Kalser, Ellenberg, Pancreatic cancer: Adjuvant combined chemotherapy following curative resection, Arch Surg, 120, pp. 899-903, (1985)

[8]

Douglas, Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer, Cancer, 59, pp. 2006-2010, (1987)

[9]

Reuben, Mor, Hiris, Clinical symptoms and length of survival in patients with terminal cancer, Arch Intern Med, 148, pp. 1586-1591, (1988)

[10]

Singh, Reber, Surgical palliation for pancreatic cancer, Surg Clin North Am, 69, pp. 599-611, (1989)

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