On the potential of oncolytic virotherapy for the treatment of canine cancers

被引：6

作者：

MacNeill, Amy L. ^{[1
]}

机构：

[1] Colorado State Univ, Coll Vet Med & Biomed Sci, Dept Microbiol Immunol & Pathol, 300 W Drake Rd, Ft Collins, CO 80523 USA

来源：

ONCOLYTIC VIROTHERAPY | 2015年 / 4卷

关键词：

oncolytic virus; cancer; canine;

D O I：

10.2147/OV.S66358

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Over 6 million dogs are diagnosed with cancer in the USA each year. Treatment options for many of these patients are limited. It is important that the veterinary and scientific communities begin to explore novel treatment protocols for dogs with cancer. Oncolytic viral therapy is a promising treatment option that may prove to be relatively inexpensive and effective against several types of cancer. The efficacy of oncolytic virus therapies has been clearly demonstrated in murine cancer models, but the positive outcomes observed in mice are not always seen in human cancer patients. These therapies should be thoroughly evaluated in dogs with spontaneously arising cancers to provide needed information about the potential effectiveness of virus treatment for human cancers and to promote the health of our companion animals. This article provides a review of the results of oncolytic virus treatment of canine cancers.

引用

页码：95 / 107

页数：13

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