GROWTH-FACTORS AND RECEPTORS IN CANCER

被引：5

作者：

HARRIS, AL ^{[1
]}

机构：

[1] UNIV OXFORD, JOHN RADCLIFFE HOSP, INST MOLEC MED, OXFORD OX3 9DU, ENGLAND

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1991年 / 2卷 / 02期

关键词：

D O I：

10.1016/0958-1669(91)90019-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

There have been a number of recent developments in mechanisms of action of growth factors and their receptors with particular relevance to cancer. The tyrosine kinase receptor family, in particular, has been shown to be important in tumour growth. These receptors are the products of oncogenes, or can interact with other oncogene pathways. Thus, antibodies to either the receptor or its ligand can be used as therapeutic agents. Peptide analogues of ligands that can block receptor activation are also potential therapeutic agents.

引用

页码：260 / 268

页数：9

共 79 条

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