MEMBRANE-ASSOCIATED CRYSTALLIZATION OF CALCIUM-OXALATE INVITRO

被引：46
作者：
KHAN, SR
SHEVOCK, PN
HACKETT, RL
机构：
[1] Department of Pathology, J-275, JHMHC, College of Medicine, University of Florida, Gainesville, 32610, Florida
来源：
CALCIFIED TISSUE INTERNATIONAL | 1990年 / 46卷 / 02期
关键词：
Calcium oxalate; Cellular membranes; Crystal nucleation; Kidney stones; Nephrolithiasis; Urolithiasis;
D O I：
10.1007/BF02556095
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Incubation of proximal tubular brush border membrane in a metastable calcium oxalate solution of low supersaturation resulted in the equimolar depletion of calcium and oxalate and the formation of monoclinic calcium oxalate crystals. We propose that membrane fragments from sloughed epithelial cells of the nephron can similarly induce crystallization in urine that is metastable for calcium oxalate. © 1990 Springer-Verlag New York Inc.
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页码：116 / 120
页数：5
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