KINETICS AND MATHEMATICAL-MODELING OF HOMOACETIC FERMENTATION OF LACTATE BY CLOSTRIDIUM-FORMICOACETICUM

被引：12

作者：

YANG, ST ^{[1
]}

TANG, IC ^{[1
]}

OKOS, MR ^{[1
]}

机构：

[1] PURDUE UNIV,DEPT AGR ENGN,W LAFAYETTE,IN 47907

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 1988年 / 32卷 / 06期

关键词：

Cell Culture--Growth Kinetics - Mathematical Models - Methane;

D O I：

10.1002/bit.260320611

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fermentation kinetics of Clostridium formicoaceticum grown on lactate at pH 7.0 and 35°C was studied. Acetate was the only fermentation product and its production was growth associated. The growth of this bacterium was insensitive to the lactate concentrations studied, but was inhibited by acetic acid. A Monod-type expression with product inhibition similar to the noncompetitive inhibition of enzyme kinetics was used to model the batch fermentation. An integrated equation was developed and used to help estimating the kinetic parameters in the model. This mathematical model can be used to simulate the homoacetic fermentation of lactate by C. formicoaceticum at pH 7.0 and 35°C.

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页码：797 / 802

页数：6

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