Osteochondral allograft transplantation for the knee

被引:0
作者
Gracitelli, G. C. [1 ,2 ]
Cohen Kaleka, C. [3 ,4 ]
Bugbee, W. D. [1 ,5 ]
机构
[1] Scripps Clin, Shiley Ctr Orthoped Res & Educ, La Jolla, CA 92037 USA
[2] Univ Fed Sao Paulo, Dept Orthoped & Traumatol, Sao Paulo, Brazil
[3] Santa Casa Sch Med, Knee Surg Div, Dept Orthopaed, Sao Paulo, Brazil
[4] Hosp Sao Paulo, Sao Paulo, Brazil
[5] Scripps Clin, Div Orthoped Surg, 10666 North Torrey Pines Rd,MS 116, La Jolla, CA 92037 USA
关键词
Knee; Cartilage; Allografts;
D O I
暂无
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Osteochondral allograft (OCA) transplantation is an effective surgical treatment option for large cartilage defects in the knee. Tissue availability and safety have had substantial development during the last years with standardization of protocols for harvesting, processing, and storage. Large cartilage lesions, cartilage lesions with bone defects, and failed previous cartilage repair are the main indicators for osteochondral allograft transplantion. Avascular necrosis, posttraumatic arthritis, and bipolar lesions represent challenging diseases and OCA transplantation has been a suitable option for treatment. Ongoing research is needed to improve the chondrocyte viability, reduce costs, reduce time for serological tests, and expand the clinical indication for osteochondral allograft transplantation.
引用
收藏
页码:75 / 86
页数:12
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