Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis

被引：6

作者：

Nakamura, Ken ^{[1
]}

Sugaya, Keizo ^{[1
]}

Nakata, Yasuhiro ^{[2
]}

Shima, Sayuri ^{[3
]}

Mutoh, Tatsuro ^{[3
]}

Nakano, Imaharu ^{[1
]}

机构：

[1] Tokyo Metropolitan Neurol Hosp, Dept Neurol, 2-6-1 Musashidai, Fuchu, Tokyo 1830042, Japan

[2] Tokyo Metropolitan Neurol Hosp, Dept Neuroradiol, Tokyo, Japan

[3] Fujita Hlth Univ, Sch Med, Dept Neurol, Toyoake, Aichi, Japan

来源：

NEUROLOGY AND CLINICAL NEUROSCIENCE | 2015年 / 3卷 / 01期

关键词：

anti-neutral glycosphingolipid antibody; encephalitis; hypertrophic pachymeningitis; relapsing polychondritis;

D O I：

10.1111/ncn3.130

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Relapsing polychondritis is a rare autoimmune multisystem disease characterized by the inflammation of cartilaginous tissues. Neurological complications with relapsing polychondritis are extremely rare. We report an 81-year-old woman with relapsing polychondritis who subsequently developed encephalitis and cognitive impairment. Brain magnetic resonance imaging showed slightly high signal intensity in the bilateral frontal dura mater using fluid-attenuated inversion recovery. T-1-weighted images with contrast enhancement showed abnormal enhancement of the dura mater, indicating hypertrophic pachymeningitis. To our knowledge, this is the first case report of relapsing polychondritis complicated by both hypertrophic pachymeningitis and encephalitis in the absence of other recognizable autoimmune diseases.

引用

页码：42 / 43

页数：2

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