INFLUENCE OF IMMUNOSUPPRESSIVE THERAPY ON T-HELPER-CELL SUBSETS IN PATIENTS WITH RHEUMATIC DISEASES

被引：0
|
作者：
BECKER, H
POTYKA, P
WEBER, C
RENELT, M
FEDERLIN, K
机构：
来源：
IMMUNITAT UND INFEKTION | 1991年 / 19卷 / 01期
关键词：
T-HELPER CELLS; IMMUNOSUPPRESSIVE THERAPY; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
To determine the influence of immunosuppressive therapy on T-helper-cell subsets in patients with systemic lupus erythematosus and rheumatoid arthritis flow cytometric analysis was performed. Longitudinal studies showed reduced numbers of CD45R+CD+ lymphocytes in patients treated with cyclophosphamide or azathioprine. Patients receiving steroids had low frequencies of CD29+CD4+ cells. The data suggest that cytotoxic drugs and steroids affect T-helper cells at different activation stages.
引用
收藏
页码：26 / 27
页数：2
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