Primary renal synovial sarcoma

被引:10
作者
Bakhshi, Cirish D. [1 ]
Khan, Arshad S. [1 ]
Shaikh, Aftab S. [1 ]
Khan, Mohammad Ashraf A. [1 ]
Khan, Mohammad Adil A. [1 ]
Jamadar, Nilofar M. [2 ]
机构
[1] Grant Med Coll & Sir JJ Grp Hosp, Dept Surg, Mumbai, Maharashtra, India
[2] Grant Med Coll & Sir JJ Grp Hosp, Dept Radiol, Mumbai, Maharashtra, India
关键词
renal tumor; synovial sarcoma;
D O I
10.4081/cp.2012.e44
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary Renal Sarcoma is rare tumor comprising only 1% of all renal tumours. Synovial sarcomas are generally deep-seated tumors arising in the proximity of large joints of adolescents and young adults and account for 5-10% of all soft tissue tumours. Primary synovial sarcoma of kidney is rare and has poor prognosis. It can only be diagnosed by immunohistochemistry. It should be considered as a differential in sarcomatoid and spindle cell tumours. We present a case of 33-year-old female, who underwent left sided radical nephrectomy for renal tumour. Histopathology and genetic analysis diagnosed it to be primary renal synovial sarcoma. Patient underwent radiation therapy and 2 years follow up is uneventful. A brief case report with review of literature is presented.
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页数:2
相关论文
共 9 条
[1]   Primary renal synovial sarcoma - Molecular and morphologic delineation of an entity previously included among embryonal sarcomas of the kidney [J].
Argani, P ;
Faria, PA ;
Epstein, JI ;
Reuter, VE ;
Perlman, EJ ;
Beckwith, JB ;
Ladanyi, M .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2000, 24 (08) :1087-1096
[2]   SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma [J].
Kawai, A ;
Woodruff, J ;
Healey, JH ;
Brennan, MF ;
Antonescu, CR ;
Ladanyi, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (03) :153-160
[3]   Analysis of SYT-SSX fusion transcripts and bcl-2 expression and phosphorylation status in synovial sarcoma [J].
Mancuso, T ;
Mezzelani, A ;
Riva, C ;
Fabbri, A ;
Dal Bo, L ;
Sampietro, G ;
Perego, P ;
Casali, P ;
Zunino, F ;
Sozzi, G ;
Pierotti, MA ;
Pilotti, S .
LABORATORY INVESTIGATION, 2000, 80 (06) :805-813
[4]  
Murphy WM, 1994, SERIES FASCICLE, V11, P219
[5]  
Park Soo-Jin, 2004, Korean Journal of Internal Medicine, V19, P62
[6]   Synovial sarcoma prognostic factors and patterns of failure [J].
Paulino, AC .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2004, 27 (02) :122-127
[7]   A novel fusion gene, SYT-SSX4, in synovial sarcoma [J].
Skytting, B ;
Nilsson, G ;
Brodin, B ;
Xie, YT ;
Lundeberg, J ;
Uhlén, M ;
Larsson, O .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (11) :974-975
[8]  
Tsai YK, 2004, CHIN J RADIOL, V29, P359
[9]  
Zia Z., 2007, INTERNET J UROLOGY, V2, P1528