THE GENOTOXICITY OF ORGANOTIN COMPOUNDS IN SOS CHROMOTEST AND REC-ASSAY

被引：27

作者：

HAMASAKI, T ^{[1
]}

SATO, T ^{[1
]}

NAGASE, H ^{[1
]}

KITO, H ^{[1
]}

机构：

[1] GIFU PHARMACEUT UNIV,DEPT PUBL HLTH,5-6-1 MITAHORAHIGASHI,GIFU 502,JAPAN

来源：

MUTATION RESEARCH | 1992年 / 280卷 / 03期

关键词：

ORGANOTIN COMPOUNDS; SOS CHROMOTEST; REC-ASSAY;

D O I：

10.1016/0165-1218(92)90049-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In these days pollution by organotin compounds in the environment extends widely and effects on human health are feared. We studied the genotoxicity of various organotin compounds (butyltins, phenyltins, methyltins) and inorganic tin (SnCl4), which are present in the environment, with the SOS chromotest and the rec-assay. Mono-n-butyltin oxide, n-butyltin trichloride and di-n-butyltin dichloride showed high SOS-inducing potency in the SOS chromotest with Escherichia coli PQ37. Di-n-butyltin dichloride, tri-n-butyltin chloride, bis(tri-n-butyltin)oxide, dimethyltin dichloride and trimethyltin chloride were recognized as genotoxic chemicals by the rec-assay.

引用

页码：195 / 203

页数：9

共 31 条

[1] BIOGEOCHEMISTRY OF BUTYLTINS IN AN ENCLOSED MARINE ECOSYSTEM [J].

ADELMAN, D ;

HINGA, KR ;

PILSON, MEQ .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1990, 24 (07) :1027-1032

[2] ENVIRONMENTAL METHYLATION OF TIN - AN ASSESSMENT [J].

ASHBY, JR ;

CRAIG, PJ .

SCIENCE OF THE TOTAL ENVIRONMENT, 1988, 73 (1-2) :127-133

[3] THE ENVIRONMENTAL DEGRADATION OF ORGANOTIN COMPOUNDS - A REVIEW [J].

BLUNDEN, SJ ;

CHAPMAN, AH .

ENVIRONMENTAL TECHNOLOGY LETTERS, 1982, 3 (06) :267-272

[4]

BOULDIN TW, 1981, AM J PATHOL, V104, P237

[5] TOXICITY OF DIBUTYLTIN, TRIBUTYLTIN AND OTHER ORGANOTIN COMPOUNDS TO HUMANS AND TO EXPERIMENTAL-ANIMALS [J].

BOYER, IJ .

TOXICOLOGY, 1989, 55 (03) :253-298

[6]

BROWN AW, 1979, AM J PATHOL, V97, P59

[7] THE FATE OF TRIBUTYLTIN IN THE AQUATIC ENVIRONMENT - A LOOK AT THE DATA [J].

CLARK, EA ;

STERRITT, RM ;

LESTER, JN .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1988, 22 (06) :600-604

[8] NATURAL VOLATILIZATION OF TIN [J].

CRAIG, P .

NATURE, 1988, 332 (6162) :309-309

[9] EVALUATION OF THE GENETIC AND EMBRYOTOXIC EFFECTS OF BIS(TRI-NORMAL-BUTYLTIN)OXIDE (TBTO), A BROAD-SPECTRUM PESTICIDE, IN MULTIPLE INVIVO AND INVITRO SHORT-TERM TESTS [J].

DAVIS, A ;

BARALE, R ;

BRUN, G ;

FORSTER, R ;

GUNTHER, T ;

HAUTEFEUILLE, H ;

VANDERHEIJDEN, CA ;

KNAAP, AGAC ;

KROWKE, R ;

KUROKI, T ;

LOPRIENO, N ;

MALAVEILLE, C ;

MERKER, HJ ;

MONACO, M ;

MOSESSO, P ;

NEUBERT, D ;

NORPPA, H ;

SORSA, M ;

VOGEL, E ;

VOOGD, CE ;

UMEDA, M ;

BARTSCH, H .

MUTATION RESEARCH, 1987, 188 (02) :65-95

[10] AN INVESTIGATION OF THE GENOTOXIC EFFECTS OF AN ORGANOTIN ANTIFOULING COMPOUND (BIS(TRIBUTYLTIN) OXIDE) ON THE CHROMOSOMES OF THE EDIBLE MUSSEL, MYTILUS-EDULIS [J].

DIXON, DR ;

PROSSER, H .

AQUATIC TOXICOLOGY, 1986, 8 (03) :185-195

← 1 2 3 4 →