Adenoma-carcinoma Sequence in the Bladder After Augmentation Cystoplasty

被引：0

作者：

Naito, Akihiro ^{[1
]}

Kawai, Taketo ^{[1
]}

Fujimura, Tetsuya ^{[1
]}

Morikawa, Teppei ^{[2
]}

Kume, Haruki ^{[1
]}

Homma, Yukio ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Urol, Tokyo, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Pathol, Tokyo, Japan

来源：

UROLOGY CASE REPORTS | 2014年 / 2卷 / 03期

关键词：

Augmentation cystoplasty; Tubulovillous adenoma; Adenoma-carcinoma sequence; Multistep carcinogenesis;

D O I：

10.1016/j.eucr.2014.01.009

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of a 64-year-old woman showing multistep progression from adenoma to adenocarcinoma in the bladder 46 years after augmentation ileocystoplasty. She underwent augmentation ileocystoplasty for tuberculous contracted bladder at 18 years. After 44 years, tubulovillous adenomas were found and resected at the ileovesical anastomosis site. After 2 more years, bladder tumors recurred and revealed adenocarcinomas. Finally, radical cystectomy was required because of frequent recurrence and tumor extensiveness. To our knowledge, this is the first case demonstrating adenoma-carcinoma sequence histopathologically in the bladder after augmentation cystoplasty, indicating multistep carcinogenesis similar to intestinal carcinogenesis. (C) 2014 The Authors. Published by Elsevier Inc. All rights reserved.

引用

页码：73 / 74

页数：2

共 9 条

[1] A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS [J].