Frequency of Early-Stage Lymphedema and Risk Factors in Postoperative Patients with Breast Cancer

被引:12
作者
Soyder, Aykut [1 ]
Tastaban, Engin [2 ]
Ozbas, Serdar [3 ]
Boylu, Sukru [1 ]
Ozgun, Hedef [1 ]
机构
[1] Adnan Menderes Univ, Fac Med, Dept Gen Surg, Aydin, Turkey
[2] Adnan Menderes Univ, Fac Med, Dept Phys Therapy & Rehabil, Aydin, Turkey
[3] Guven Hosp, Dept Gen Surg, Ankara, Turkey
来源
JOURNAL OF BREAST HEALTH | 2014年 / 10卷 / 02期
关键词
Lymphedema; breast cancer; risk factors; incidence;
D O I
10.5152/tjbh.2014.1973
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective: Lymphedema is a chronic major complication that is seen frequently post-operatively and has negative effects on quality of life. In our study, determining the early-stage postoperative lymphedema frequency and specifying the risk factors in its development has been aimed. Materials and Methods: One hundred one cases that were operated on for breast cancer were evaluated regarding the 12-month control of their clinical specifications, histopathological specifications, and specifications related with the surgical intervention retrospectively. The data related to the parameters envisioned as risk factors were evaluated. Results: Lymphedema development was found in 7 (6.9%) out of 101 cases constituting the study group. No significant difference (p> 0.05) in terms of lymphedema development was determined among age, body mass index (BMI), chemotherapy (CT), postoperative seroma or infection, mastectomy with the dominant arm, and breast-conserving surgery (BCS), which were evaluated as risk factors. There was a significance (p< 0.05) between the other risk factors, which were axillary dissection (AD), number of positive lymph nodes (LN), radiotherapy (RT), the tumor size (T), and lymphedema existence. In every case in which lymphedema was determined, it was seen that there was axillary LN involvement and 15=LN were ablated in the dissection (p< 0.05). Conclusion: It is seen that AD, RT applied to the breast cancer patients, and T are important risk factors in early-stage lymphedema development. No earlystage lymphedema development was determined in any of the patients to whom sentinel lymph node dissection (SLND) was applied.
引用
收藏
页码:92 / 97
页数:6
相关论文
共 43 条
[1]   Risk factors for developing upper limb lymphedema after breast cancer treatment [J].
Arrault, Maria ;
Vignes, Stephane .
BULLETIN DU CANCER, 2006, 93 (10) :1001-1006
[2]   Relapse and morbidity in patients undergoing sentinel lymph node biopsy alone or with axillary dissection for breast cancer [J].
Blanchard, DK ;
Donohue, JH ;
Reynolds, C ;
Grant, CS .
ARCHIVES OF SURGERY, 2003, 138 (05) :482-487
[3]   Incidence and risk of arm oedema following treatment for breast cancer: a three-year follow-up study [J].
Clark, B ;
Sitzia, J ;
Harlow, W .
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2005, 98 (05) :343-348
[4]   An audit of the incidence of arm lymphoedema after prophylactic level I/II axillary dissection without division of the pectoralis minor muscle [J].
della Rovere, GQ ;
Ahmad, I ;
Singh, P ;
Ashley, S ;
Daniels, IR ;
Mortimer, P .
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2003, 85 (03) :158-161
[5]  
Deo S V S, 2004, Indian J Cancer, V41, P8
[6]   Arm edema after lumpectomy and breast irradiation [J].
Deutsch, M ;
Flickinger, JC .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2003, 26 (03) :229-231
[7]   Prevalence and aetiology of lymphoedema after breast cancer treatment in southern Tasmania [J].
Edwards, TL .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 2000, 70 (06) :412-418
[8]   Arm edema in breast cancer patients [J].
Erickson, VS ;
Pearson, ML ;
Ganz, PA ;
Adams, J ;
Kahn, KL .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2001, 93 (02) :96-111
[9]   Factors associated with arm swelling after breast cancer surgery [J].
Geller, BM ;
Vacek, PM ;
O'Brien, P ;
Secker-Walker, RH .
JOURNAL OF WOMENS HEALTH, 2003, 12 (09) :921-930
[10]  
Gerber LH, 1998, CANCER, V83, P2803, DOI 10.1002/(SICI)1097-0142(19981215)83:12B+<2803::AID-CNCR29>3.3.CO