DEPRESSION FOLLOWING TRAUMATIC BRAIN INJURY - A 1 YEAR LONGITUDINAL-STUDY

被引：181

作者：

JORGE, RE

ROBINSON, RG

ARNDT, SV

STARKSTEIN, SE

FORRESTER, AW

GEISLER, F

机构：

[1] UNIV IOWA,COLL MED,DEPT PSYCHIAT,IOWA CITY,IA 52242

[2] UNIV IOWA,MENTAL HLTH CLIN RES CTR,BIOSTAT CORE UNIT,IOWA CITY,IA 52242

[3] INST NEUROL INVEST,DR RAUL CARREA,DEPT BEHAV NEUROL,BUENOS AIRES,ARGENTINA

[4] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,BALTIMORE,MD 21205

[5] UNIV MARYLAND,MARYLAND INST EMERGENCY MED SERV SYST,CTR SHOCK TRAUMA,DEPT SURG,BALTIMORE,MD 21201

来源：

JOURNAL OF AFFECTIVE DISORDERS | 1993年 / 27卷 / 04期

关键词：

MAJOR DEPRESSION; TRAUMATIC BRAIN INJURY;

D O I：

10.1016/0165-0327(93)90047-N

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A group of 66 patients hospitalized for the treatment of closed head injury, were assessed for the presence of mood disorders during their hospital admission and at 3, 6 and 12 months follow-up. A total 28 patients met DSM-III-R diagnostic criteria for major depression at some time during the study (17 in the acute stage, 11 during follow-up). The mean duration of major depression was 4.7 months. However, there appeared to be a group of transiently depressed patients (41%) who where depressed inhospital but were no longer depressed at 3 months follow-up. Throughout the follow-up period, major depression showed a strong relationship with poor social functioning. There was not, however, a consistent relationship between depression and quantitative measures of either physical or cognitive impairment. Location of the brain lesion was associated with the development of major depression only in the acute stage. Transient depressive syndromes were associated with left dorsolateral frontal and/or left basal ganglia lesions.

引用

页码：233 / 243

页数：11