VALPROATE METABOLITES AND HEPATOTOXICITY IN AN EPILEPTIC POPULATION

被引：36

作者：

TENNISON, MB ^{[1
]}

MILES, MV ^{[1
]}

POLLACK, GM ^{[1
]}

THORN, MD ^{[1
]}

DUPUIS, RE ^{[1
]}

机构：

[1] UNIV N CAROLINA,SCH PHARM,CHAPEL HILL,NC 27599

来源：

EPILEPSIA | 1988年 / 29卷 / 05期

关键词：

D O I：

10.1111/j.1528-1157.1988.tb03758.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：543 / 547

页数：5

共 25 条

[1] INHIBITION OF MEDIUM-CHAIN FATTY-ACID BETA-OXIDATION INVITRO BY VALPROIC ACID AND ITS UNSATURATED METABOLITE, 2-NORMAL-PROPYL-4-PENTENOIC ACID [J].

BJORGE, SM ;

BAILLIE, TA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 132 (01) :245-252

[2] PROTECTION AGAINST SODIUM VALPROATE INJURY IN ISOLATED HEPATOCYTES BY ALPHA-TOCOPHEROL AND "N,N'-DIPHENYL-PARA-PHENYLENEDIAMINE [J].

BUCHI, KN ;

GRAY, PD ;

ROLLINS, DE ;

TOLMAN, KG .

JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 24 (04) :148-154

[3] ACTION OF THE ANTI-EPILEPTIC DRUG, VALPROIC ACID, ON FATTY-ACID OXIDATION IN ISOLATED RAT HEPATOCYTES [J].

COUDE, FX ;

GRIMBER, G ;

PELET, A ;

BENOIT, Y .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 115 (02) :730-736

[4] PHARMACOLOGY OF VALPROIC ACID IN CHILDREN WITH SEVERE EPILEPSY - CLEARANCE AND HEPATOTOXICITY [J].

DODSON, WE ;

TASCH, V .

NEUROLOGY, 1981, 31 (08) :1047-1050

[5] VALPROIC ACID HEPATIC FATALITIES - A RETROSPECTIVE REVIEW [J].

DREIFUSS, FE ;

SANTILLI, N ;

LANGER, DH ;

SWEENEY, KP ;

MOLINE, KA ;

MENANDER, KB .

NEUROLOGY, 1987, 37 (03) :379-385

[6] THE HEPATOTOXICITY OF VALPROIC ACID AND ITS METABOLITES IN RATS .2. INTERMEDIARY AND VALPROIC ACID METABOLISM [J].

GRANNEMAN, GR ;

WANG, SI ;

KESTERSON, JW ;

MACHINIST, JM .

HEPATOLOGY, 1984, 4 (06) :1153-1158

[7] SODIUM VALPROATE AND ROUTINE LIVER-FUNCTION TESTS [J].

GREEN, SH .

ARCHIVES OF DISEASE IN CHILDHOOD, 1984, 59 (09) :813-814

[8]

HEINMEYER G, 1984, BIOCH PHARM

[9] NON-DOSE-RELATED SIDE-EFFECTS OF VALPROATE [J].

JEAVONS, PM .

EPILEPSIA, 1984, 25 :S50-S55

[10] THE HEPATOTOXICITY OF VALPROIC ACID AND ITS METABOLITES IN RATS .1. TOXICOLOGIC, BIOCHEMICAL AND HISTOPATHOLOGIC STUDIES [J].

KESTERSON, JW ;

GRANNEMAN, GR ;

MACHINIST, JM .

HEPATOLOGY, 1984, 4 (06) :1143-1152

← 1 2 3 →