Toxoplasmosis: A global threat

被引:133
作者
Furtado, Joaeo M. [1 ]
Smith, Justine R. [2 ,3 ]
Belfort, Rubens, Jr. [4 ]
Gattey, Devin [1 ]
Winthrop, Kevin L. [1 ]
机构
[1] Oregon Hlth & Sci Univ, Casey Eye Inst, Div Int Ophthalmol, Portland, OR 97201 USA
[2] Oregon Hlth & Sci Univ, Casey Eye Inst, Portland, OR 97201 USA
[3] Oregon Hlth & Sci Univ, Dept Cell & Dev Biol, Portland, OR 97201 USA
[4] Univ Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
关键词
Congenital toxoplasmosis; Ocular toxoplasmosis; Toxoplasmic encephalitis;
D O I
10.4103/0974-777X.83536
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Toxoplasmosis, a disease described worldwide, which is caused by the protozoan Toxoplasma gondii, commonly involves the retina. The disease has a higher impact in immunocompromised individuals and in congenital infection because of the severity of central nervous system involvement. Although simple prophylactic measures could reduce transmission, T. gondii seroprevalence is still high, especially in South America. Educational campaigns and the development of new drugs to prevent primary infection could potentially reduce the burden of the disease.
引用
收藏
页码:281 / 284
页数:4
相关论文
共 53 条
[1]   Outbreak of Acquired Ocular Toxoplasmosis Involving 248 Patients [J].
Balasundaram, Manohar B. ;
Andavar, Raghuram ;
Palaniswamy, Manikandan ;
Venkatapathy, Narendran .
ARCHIVES OF OPHTHALMOLOGY, 2010, 128 (01) :28-32
[2]   Lytic cycle of Toxoplasma gondii [J].
Black, MW ;
Boothroyd, JC .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2000, 64 (03) :607-+
[3]   Ocular toxoplasmosis - Clinical features and prognosis of 154 patients [J].
Bosch-Driessen, LEH ;
Berendschot, TTJM ;
Ongkosuwito, JV ;
Rothova, A .
OPHTHALMOLOGY, 2002, 109 (05) :869-878
[4]   Outbreak of toxoplasmosis associated with municipal drinking water [J].
Bowie, WR ;
King, AS ;
Werker, DH ;
IsaacRenton, JL ;
Bell, A ;
Eng, SB ;
Marion, SA .
LANCET, 1997, 350 (9072) :173-177
[5]   Foodborne outbreaks of human toxoplasmosis [J].
Choi, WY ;
Nam, HW ;
Kwak, NH ;
Huh, W ;
Kim, YR ;
Kang, MW ;
Cho, SY ;
Dubey, JP .
JOURNAL OF INFECTIOUS DISEASES, 1997, 175 (05) :1280-1282
[6]  
Contini C., 2008, Parassitologia (Rome), V50, P45
[7]   CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain [J].
Courret, N ;
Darche, S ;
Sonigo, P ;
Milon, G ;
Buzoni-Gâtel, D ;
Tardieux, I .
BLOOD, 2006, 107 (01) :309-316
[8]   Waterborne toxoplasmosis, Brazil, from field to gene [J].
de Moura, L ;
Bahia-Oliveira, LMG ;
Wada, MY ;
Jones, JL ;
Tuboi, SH ;
Carmo, EH ;
Ramalho, WM ;
Camargo, NJ ;
Trevisan, R ;
Graça, RMT ;
da Silva, AJ ;
Moura, I ;
Dubey, JP ;
Garrett, DO .
EMERGING INFECTIOUS DISEASES, 2006, 12 (02) :326-329
[9]   Prevention of toxoplasmosis in transplant patients [J].
Derouin, F. ;
Pelloux, H. .
CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 (12) :1089-1101
[10]   Ocular Sequelae of Congenital Toxoplasmosis in Brazil Compared with Europe [J].
Gilbert, Ruth E. ;
Freeman, Katherine ;
Lago, Eleonor G. ;
Bahia-Oliveira, Lilian M. G. ;
Tan, Hooi Kuan ;
Wallon, Martine ;
Buffolano, Wilma ;
Stanford, Miles R. ;
Petersen, Eskild .
PLOS NEGLECTED TROPICAL DISEASES, 2008, 2 (08)