OCULAR HERPES-SIMPLEX VIRUS-INFECTIONS - REDUCED SENSITIVITY TO ACYCLOVIR IN PRIMARY DISEASE

被引：15

作者：

CHARLES, SJ

GRAY, JJ

机构：

[1] ADDENBROOKES HOSP, CLIN MICROBIOL & PUBL HLTH LAB, CAMBRIDGE CB2 2QQ, ENGLAND

[2] ADDENBROOKES HOSP, DEPT OPHTHALMOL, CAMBRIDGE CB2 2QQ, ENGLAND

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1990年 / 74卷 / 05期

关键词：

D O I：

10.1136/bjo.74.5.286

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Forty isolates of herpes simplex virus (HSV) obtained from ocular herpetic infections were assayed for their sensitivity to five antiviral agents. There were wide ranges of sensitivity to foscarnet, idoxuridine, and vidarabine, but the majority were sensitive to acyclovir and ganciclovir. Reduced sensitivity to acyclovir was seen in four isolates, all of which were from primary infections acquired in the community and without a previous history of treatment with antiviral drugs.

引用

页码：286 / 288

页数：3

共 14 条

[1]

BURNS WH, 1982, LANCET, V1, P421

[2]

CHENG YC, 1983, J BIOL CHEM, V258, P2460

[3] ORAL ACYCLOVIR (ZOVIRAX) IN HERPES-SIMPLEX DENDRITIC CORNEAL ULCERATION [J].