FLUCONAZOLE;
HUMAN IMMUNODEFICIENCY VIRUS;
TOXIC EPIDERMAL NECROLYSIS;
D O I:
10.1159/000247261
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
Patients with human immunodeficiency virus (HIV) infection are prone to severe drug reactions, mainly from sulfonamides. We report the case of a 33-year-old male patient with HIV infection (group IV C-2 of CDC staging system) that developed a toxic epidermal necrolysis (TEN) affecting more than 70% of the body surface area and severe mucosal involvement after starting fluconazole for a recurrent oral thrush with dysphagia. This is to our knowledge the first reported case of TEN due to fluconazole.