FLUCONAZOLE-INDUCED TOXIC EPIDERMAL NECROLYSIS IN A PATIENT WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

被引:23
作者
AZONMASOLIVER, A [1 ]
VILAPLANA, J [1 ]
机构
[1] HOSP ST JOAN,DEPT DERMATOL,REUS,SPAIN
关键词
FLUCONAZOLE; HUMAN IMMUNODEFICIENCY VIRUS; TOXIC EPIDERMAL NECROLYSIS;
D O I
10.1159/000247261
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Patients with human immunodeficiency virus (HIV) infection are prone to severe drug reactions, mainly from sulfonamides. We report the case of a 33-year-old male patient with HIV infection (group IV C-2 of CDC staging system) that developed a toxic epidermal necrolysis (TEN) affecting more than 70% of the body surface area and severe mucosal involvement after starting fluconazole for a recurrent oral thrush with dysphagia. This is to our knowledge the first reported case of TEN due to fluconazole.
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页码:268 / 269
页数:2
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