CHEMICAL ALTERATION OF NUCLEIC-ACIDS AND THEIR COMPONENTS .13. REACTION OF NUCLEOSIDES WITH DIACYL PEROXIDES

被引：16

作者：

ARAKI, M ^{[1
]}

MAEDA, M ^{[1
]}

KAWAZOE, Y ^{[1
]}

机构：

[1] NATL CANC CTR, RES INST, CHUO 104, TOKYO, JAPAN

来源：

TETRAHEDRON | 1976年 / 32卷 / 03期

关键词：

D O I：

10.1016/0040-4020(76)80046-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diacyl peroxides reacted at room temperature with cytidine and adenosine. The former gave 4-acyl and 3-oxido derivatives, and the latter gave 6-acyl and 1-oxido derivatives. At 90.degree. C diacetyl peroxide reacted with guanosine, adenosine, cytidine and uridine by a homolytic process to give their C-methylated derivatives. The latter reaction was accelerated by the presence of a ferrous ion.

引用

页码：337 / 340

页数：4

共 23 条

[1]

AIWA M, 1974, CHEM PHARM BULL, V22, P2979

[2]

CRAMER F, 1963, BIOCHIM BIOPHYS ACTA, V72, P150

[3]

CRAMMER F, 1963, BIOCHIM BIOPHYS ACTA, V72, P157

[4] CYTOSINE 3-N-OXIDE AND ITS REARRANGEMENT ON ACETYLATION [J].