LOCALIZATION OF A VITAMIN-D-BINDING PROTEIN-INTERACTION SITE IN THE COOH-TERMINAL SEQUENCE OF ACTIN

被引：17
作者：
HOUMEIDA, A
HANIN, V
CONSTANS, J
BENYAMIN, Y
ROUSTAN, C
机构：
[1] UNIV MONTPELLIER 1,MOTILITE CELLULAIRE LAB,INSERM,CNRS,U249,CTR RECH BIOCHIM MACROMOLEC,UPR 8402,F-34033 MONTPELLIER,FRANCE
[2] CHU PURPAN,CNRS,CRPG,TOULOUSE,FRANCE
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1992年 / 203卷 / 03期
关键词：
D O I：
10.1111/j.1432-1033.1992.tb16575.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The serum vitamin D binding protein is the carrier of vitamin D and its derivatives in the plasma. One of the known roles of this protein is to sequester monomeric actin in the blood, therefore implicating this protein in actin elimination. However, its binding site at the surface of actin is poorly delimited. We report here the results of a study which locates, using several actin fragments together with immunological probes, a vitamin D binding protein site near the COOH-terminal extremity. Thus, the interface is delimited by the sequence 360-372 in subdomain I of actin.
引用
收藏
页码：499 / 503
页数：5
相关论文
共 37 条
  • [1] ANTIACTIN ANTIBODIES - CHEMICAL MODIFICATION ALLOWS THE SELECTIVE PRODUCTION OF ANTIBODIES TO THE N-TERMINAL REGION
    BENYAMIN, Y
    ROUSTAN, C
    BOYER, M
    [J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1986, 86 (01) : 21 - 29
  • [2] IMMUNOCHEMISTRY OF LOBSTER ARGININE KINASE - EFFECT OF CHEMICAL MODIFICATIONS OF ESSENTIAL AMINO-ACID RESIDUES ON ANTIGENIC REACTIVITY
    BENYAMIN, Y
    ROBIN, Y
    VANTHOAI, N
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 37 (03): : 459 - 466
  • [3] ANTIGENIC PROBES LOCATE A SERUM-GELSOLIN-INTERACTION SITE ON THE C-TERMINAL PART OF ACTIN
    BOYER, M
    FEINBERG, J
    HUE, HK
    CAPONY, JP
    BENYAMIN, Y
    ROUSTAN, C
    [J]. BIOCHEMICAL JOURNAL, 1987, 248 (02) : 359 - 364
  • [4] DNASE-I - ACTIN COMPLEX - AN IMMUNOLOGICAL STUDY
    BOYER, M
    ROUSTAN, C
    BENYAMIN, Y
    [J]. BIOSCIENCE REPORTS, 1985, 5 (01) : 39 - 46
  • [5] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
  • [6] EFFECTS OF SERUM VITAMIN-D-BINDING PROTEIN ON ACTIN IN THE PRESENCE OF PLASMA GELSOLIN
    COUE, M
    CONSTANS, J
    OLOMUCKI, A
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1986, 160 (02): : 273 - 277
  • [7] THE EFFECT OF SERUM VITAMIN-D-BINDING PROTEIN ON POLYMERIZATION AND DEPOLYMERIZATION OF ACTIN IS SIMILAR TO THE EFFECT OF PROFILIN ON ACTIN
    COUE, M
    CONSTANS, J
    VIAU, M
    OLOMUCKI, A
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 759 (03) : 137 - 145
  • [8] GROUP-SPECIFIC COMPONENT (GC) PROTEINS BIND VITAMIN-D AND 25-HYDROXYVITAMIN-D
    DAIGER, SP
    SCHANFIELD, MS
    CAVALLISFORZA, LL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (06) : 2076 - 2080
  • [9] ANTIBODY AGAINST THE AMINO TERMINUS OF ALPHA-ACTIN INHIBITS ACTOMYOSIN INTERACTIONS IN THE PRESENCE OF ATP
    DASGUPTA, G
    REISLER, E
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1989, 207 (04) : 833 - 836
  • [10] UPTAKE AND DEGRADATION OF VITAMIN-D BINDING-PROTEIN AND VITAMIN-D BINDING-PROTEIN ACTIN COMPLEX INVIVO IN THE RAT
    DUELAND, S
    BLOMHOFF, R
    PEDERSEN, JI
    [J]. BIOCHEMICAL JOURNAL, 1990, 267 (03) : 721 - 725
1234