STUDY TO ASSESS THE EFFECTIVENESS AND SIDE EFFECT OF DILTIAZEM 2% GEL IN THE MANAGEMENT OF CHRONIC FISSURE-IN-ANO

OBJECTIVE: To know the effectiveness and side effect of diltiazem 2% gel in the management of chronic fissure-in-ano. MATERIALS AND METHODS: Prospective study was undertaken at Department of general surgery, Gold Field Medical College and Research Centre, Chhainsa, Ballabhgarh, Haryana from January 2012 to January 2014. 84 patients with only primary fissure-in-ano and in which fissure symptoms not relieved in 8 weeks were treated in this study. RESULT: Study shows male predominance. 60.7% were males 39.3% were females. 76% patients were in age group between 25 to 35 yrs. posterior fissure was in 82.1% of cases and anterior in 17.9% of cases. Fissure healing with pain relief was in 90.4% cases. In 9.6% cases fissure symptoms were not relieved, such patients were treated surgically using lateral internal sphincterotomy with sentinel tag excision. In 2.3% cases had headache and palpitation in 0% cases. CONCLUSION: After doing this study we conclude that one should initially manage the cases of chronic fissure-in-ano with, diltiazem 2% gel before opting any surgical procedure for it.