CELLULAR ORIGINS OF AUTOANTIBODY - PERPLEXING QUESTION

被引:13
作者
BANKHURST, AD [1 ]
WILLIAMS, RC [1 ]
机构
[1] UNIV NEW MEXICO, BERNALILLO CTY MED CTR, SCH MED, DEPT MED, ALBUQUERQUE, NM 87131 USA
关键词
D O I
10.1016/0002-9343(76)90364-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The potential for the emergence of autoimmunity presumably exists within all normal subjects. The B [bone marrow derived] lymphocytes reactive with self-components may be held in abeyance only by the absence of stimulation from a T [thymus derived] cell helper consort. The unleashing of autoimmunity could arise by the intercession of a B cell stimulant by 1 of several bypass mechanisms which circumvent the need for autoantigen specific T lymphocytes.
引用
收藏
页码:303 / 307
页数:5
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