THE INCIDENCE OF HUMAN PARVOVIRUS B19 INFECTION DURING PREGNANCY AND ITS IMPACT ON PERINATAL OUTCOME

被引：117

作者：

GRATACOS, E

TORRES, PJ

VIDAL, J

ANTOLIN, E

COSTA, J

DEANTA, MTJ

CARARACH, V

ALONSO, PL

FORTUNY, A

机构：

[1] UNIV BARCELONA,HOSP CLIN,DEPT OBSTET & GINECOL,BARCELONA,SPAIN

[2] UNIV BARCELONA,HOSP CLIN,DEPT MICROBIOL,EPIDEMIOL UNIT,BARCELONA,SPAIN

来源：

JOURNAL OF INFECTIOUS DISEASES | 1995年 / 171卷 / 05期

关键词：

D O I：

10.1093/infdis/171.5.1360

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A prospective study of parvovirus B19 infection during pregnancy was conducted at a large teaching hospital in Barcelona, Spain. Women (1610) who were <28 weeks pregnant at enrollment were screened for parvovirus infection. The prevalence of IgG positivity was 35.03% (564/1610). The incidence of acute infection during pregnancy was 3.7% (60/1610), There were five abortions among the B19-infected women but only one was caused by parvovirus, as assessed by histologic examination and polymerase chain reaction assay. The incidence of fetal loss caused by parvovirus was, therefore, 1.66% (1/60). The remaining 55 pregnancies were uneventful, and at 1 year of age, none of the infants had serious abnormalities. The incidence of vertical transmission of infection was estimated at 25%. This study provides evidence that although acute parvovirus infection may occur relatively commonly during pregnancy, an adverse fetal outcome is a rare complication.

引用

页码：1360 / 1363

页数：4

共 14 条

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