PHENACETIN O-DEETHYLASE - AN ACTIVITY OF A CYTOCHROME-P-450 SHOWING GENETIC-LINKAGE WITH THAT CATALYZING THE 4-HYDROXYLATION OF DEBRISOQUINE

被引：34

作者：

KAHN, GC ^{[1
]}

BOOBIS, AR ^{[1
]}

BRODIE, MJ ^{[1
]}

TOVERUD, EL ^{[1
]}

MURRAY, S ^{[1
]}

DAVIES, DS ^{[1
]}

机构：

[1] ROYAL POSTGRAD MED SCH,DEPT CLIN PHARMACOL,LONDON W12 0HS,ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1985年 / 20卷 / 01期

关键词：

D O I：

10.1111/j.1365-2125.1985.tb02800.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：67 / 76

页数：10

共 25 条

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[6] GENETIC-POLYMORPHISM IN DRUG OXIDATION - INVITRO STUDIES OF HUMAN DEBRISOQUINE 4-HYDROXYLASE AND BUFURALOL 1'-HYDROXYLASE ACTIVITIES [J].

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[7] BIPHASIC O-DEETHYLATION OF PHENACETIN AND 7-ETHOXYCOUMARIN BY HUMAN AND RAT-LIVER MICROSOMAL FRACTIONS [J].

BOOBIS, AR ;

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[8] EVIDENCE FOR AN ENZYMATIC DEFECT IN THE 4-HYDROXYLATION OF DEBRISOQUINE BY HUMAN-LIVER [J].

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