AMNIOTIC-FLUID REACTIVITY DETECTED BY SOMATOMEDIN C RADIORECEPTOR ASSAY - CORRELATION WITH GROWTH-HORMONE, PROLACTIN AND FETAL RENAL MATURATION

被引：57
作者：
CHOCHINOV, RH
KETUPANYA, A
MARIZ, IK
UNDERWOOD, LE
DAUGHADAY, WH
机构：
[1] WASHINGTON UNIV, SCH MED, DEPT OBSTET & GYNECOL, PERINATAL UNIT, ST LOUIS, MO 63110 USA
[2] UNIV N CAROLINA, DEPT PEDIAT, CHAPEL HILL, NC 27514 USA
[3] WASHINGTON UNIV, SCH MED, DEPT MED, DIV METAB, ST LOUIS, MO 63110 USA
来源：
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1976年 / 42卷 / 05期
关键词：
D O I：
10.1210/jcem-42-5-983
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Amniotic fluid was assayed by a radioreceptor assay utilizing 125I-somatomedin C and placental membranes. Growth hormone and prolactin levels were measured by radioimmunoassay at different gestational ages (8-41 wk). Somatomedin receptor activity, growth hormone and prolactin reached high levels during early gestation (8-26 wk) displaying different patterns of appearance which reflect fetal serum levels of these hormones. After 26 wk gestation all these hormones decreased in concentration. This decrease showed a strong correlation with [human] fetal renal maturation as measured by amniotic fluid creatinine levels.
引用
收藏
页码：983 / 986
页数：4
相关论文
共 17 条
[1]   ONTOGENESIS OF HUMAN FETAL HORMONES .3. PROLACTIN [J].
AUBERT, ML ;
GRUMBACH, MM ;
KAPLAN, SL .
JOURNAL OF CLINICAL INVESTIGATION, 1975, 56 (01) :155-164
[2]   PATTERN OF HUMAN CHORIONIC SOMATOMAMMOTROPIC (HCS) CONCENTRATION RATIO IN MATERNAL SERUM AND AMNIOTIC-FLUID DURING NORMAL-PREGNANCY [J].
BERLE, P .
ACTA ENDOCRINOLOGICA, 1974, 76 (02) :364-368
[3]  
BONSNES RW, 1945, J BIOL CHEM, V158, P581
[4]  
CHOCHINOV RH, 1975, 57TH P ANN M END SOC, P115
[5]   STUDIES ON HUMAN SEXUAL DEVELOPMENT .3. FETAL PITUITARY AND SERUM, AND AMNIOTIC-FLUID CONCENTRATIONS OF LH, CG, AND FSH [J].
CLEMENTS, JA ;
REYES, FI ;
WINTER, JSD ;
FAIMAN, C .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1976, 42 (01) :9-19
[6]  
HARRISON RF, 1973, J OBSTET GYN BR COMM, V80, P338
[7]   RADIORECEPTOR AND RADIOIMMUNOASSAY QUANTITATION OF HUMAN GROWTH-HORMONE IN ACROMEGALIC SERUM - OVERESTIMATION BY IMMUNOASSAY AND SYSTEMATIC DIFFERENCES BETWEEN ANTISERA [J].
HERINGTON, AC ;
JACOBS, LS ;
DAUGHADAY, WH .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1974, 39 (02) :257-262
[8]  
HONDA KS, 1969, J JAP OBSTET GYNECOL, V21, P1133
[9]   TOTAL PROTEIN CONTENT IN AMNIOTIC-FLUID FROM NORMAL PREGNANCIES AND FROM PREGNANCIES COMPLICATED BY RH-ISOIMMUNIZATION [J].
JONASSON, LE .
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 1972, 51 (02) :187-+
[10]   ONTOGENESIS OF HUMAN FETAL HORMONES .1. GROWTH-HORMONE AND INSULIN [J].
KAPLAN, SL ;
SHEPARD, TH ;
GRUMBACH, MM .
JOURNAL OF CLINICAL INVESTIGATION, 1972, 51 (12) :3080-&
12