PRESENCE OF AMELANOTIC MELANOCYTES WITHIN THE OUTER ROOT SHEATH IN SENILE WHITE HAIR

被引：22

作者：

TAKADA, K ^{[1
]}

SUGIYAMA, K ^{[1
]}

YAMAMOTO, I ^{[1
]}

OBA, K ^{[1
]}

TAKEUCHI, T ^{[1
]}

机构：

[1] TOHOKU UNIV,INST BIOL,SENDAI,MIYAGI 980,JAPAN

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1992年 / 99卷 / 05期

关键词：

D O I：

10.1111/1523-1747.ep12668031

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In order to determine whether amelanotic melanocytes are present in senile white hair, we attempted to detect tyrosinase mRNA and its protein using in situ hybridization and immunohistochemical staining. Specifically stained cells containing tyrosinase mRNA or its protein were detected by each technique in 7/23 (30.4%) or 4/14 (28.6%) senile white hairs, respectively. These cells were located in the outer root sheath between the hair-bulb and the infundibulum. Silver staining was used to determine whether melanin was present within the outer root sheath of the senile white hair. Because none of the 21 white hairs tested showed specific staining within the outer root sheath, the absence of melanin was confirmed. Thus our results suggest the presence of amelanotic melanocytes within the outer root sheath of senile white hair.

引用

页码：629 / 633

页数：5

共 24 条

[1]

Birbeck MCS, 1959, PIGMENT CELL BIOLOGY, P549

[2] THE GRAYING OF HAIR [J].