POTENTIAL ANTITUMOR AGENTS .9. BISQUATERNARY SALTS

被引：9

作者：

CAIN, BF

ATWELL, GJ

SEELYE, RN

机构：

[1] Cancer Chemotherapy Laboratory, Cornwall Geriatric Hospital, Auckland

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1968年 / 11卷 / 05期

关键词：

D O I：

10.1021/jm00311a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The postulate that a close approach to over-all planarity in bisquaternary ammonium heterocycles is essential for maximum activity when tested against the L1210 system has been further investigated. The preparation of L1210 active quaternary salts containing a diphenyl system suggests that complete planarity in this type of molecule is not an essential requirement. © 1968, American Chemical Society. All rights reserved.

引用

页码：963 / &

共 7 条

[1] POTENTIAL ANTITUMOR AGENTS .6. BISQUATERNARY SALTS [J].

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) :295-&

[2] POTENTIAL ANTITUMOR AGENTS .V. BISQUATERNARY SALTS [J].

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (04) :706-&

[3] POTENTIAL ANTITUMOR AGENTS .8. BISQUATERNARY SALTS [J].

ATWELL, GJ ;

CAIN, BF ;

SEELYE, RN .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) :690-&

[4]

BENNETT LL, 1965, PROG EXP TUMOR RES, V7, P259

[5]

CAIN BF, 1968, J MED CHEM, V11, P300

[6]

HIRT R, 1964, CHEMOTHERAPY CANCER, P228

[7]

PLATTNER A, 1964, CHEMOTHERAPY CANC ED, P228

← 1 →