Epidemiology, risk groups and prevention of choriocarcinoma

The incidence of choriocarcinoma in Georgia in 1965-1992 comprised 0,3 per 100.000 women. Rates of morbidity varied from 0 to 0.6 depending on the place of residence, age and nationality. Clinical evidence (1977-1992) show that in the group of trophoblastic disease (n=457) chorioncarcinoma occupies the place immediately below cyctic mole (26.5% and 57.1%, respectively). In 8 (6,6%) cases it was not associated with pregnancy. Six optional and one obligatory risk factors were established. List of choriocarcinoma risk factors was made. Patients were assigned to risk groups in the presence of four corresponding factors. The formation of the risk groups and prophylactic medical examination take place in the local maternity welfare clinics.