DIFFERENCES IN SERUM INTERLEUKIN-6 (IL-6) BETWEEN HEALTHY DEXTRAL AND NON-DEXTRAL SUBJECTS

被引:0
|
作者
CHENGAPPA, KNR
GANGULI, R
YANG, ZW
SCHURIN, G
BRAR, JS
ROSENBLEET, JA
RABIN, BS
机构
[1] UNIV PITTSBURGH,SCH MED,DEPT PATHOL,DIV IMMUNOPATHOL,PITTSBURGH,PA
[2] UNIV PITTSBURGH,CTR BRAIN BEHAV & IMMUN,PITTSBURGH,PA
[3] CARNEGIE MELLON UNIV,PITTSBURGH,PA 15213
关键词
CEREBRAL ASYMMETRY; HANDEDNESS; ELISA; INTERLEUKIN-6; AUTOIMMUNITY;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Serum interleukin-6 (IL-6) was measured in picograms/ml (pg/ml) using an immunoassay (ELISA) in healthy individuals (n = 148), of whom 128 were classified as dextral and 20 as non-dextral, as per a laterality questionnaire. Only 3 (15%) non-dextral individuals had serum IL-6 levels above the lower limit of the assay sensitivity as compared to 59 (46%) of dextral individuals (P < 0.013). There were no significant correlations between previously determined mitogen stimulated interleukin-2 production and autoantibodies in a subset of the same individuals. While this data does not provide casual information, it adds to the evidence of the asymmetric regulation of immune functions by the cerebral hemispheres.
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页码:185 / 188
页数:4
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