HEAT-SHOCK PROTEINS AND JUVENILE CHRONIC ARTHRITIS

被引：0

作者：

DEGRAEFFMEEDER, ER ^{[1
]}

VANEDEN, W ^{[1
]}

RIJKERS, GT ^{[1
]}

PRAKKEN, BJ ^{[1
]}

ZEGERS, BJM ^{[1
]}

KUIS, W ^{[1
]}

机构：

[1] UNIV UTRECHT,FAC VET,DEPT INFECT DIS & IMMUNOL,UTRECHT,NETHERLANDS

来源：

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 1993年 / 11卷

关键词：

HEAT SHOCK PROTEINS; JUVENILE CHRONIC ARTHRITIS; T-CELL IMMUNITY;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heat-shock proteins are a category of proteins that are synthesized under stressful conditions (such as increased temperatures) both by prokaryotic and eukaryotic cells. Heat-shock proteins are a major target of the immune response and thus can be considered dominant antigens. Under physiological circumstances the response to heat-shock proteins is considered to play a role in the overall defence against bacterial infections. An aberrant immune response against heat-shock proteins may lead to autoimmunity, as illustrated by adjuvant arthritis in Lewis rats. Current evidence also points towards a role of T cell immunity against heat-shock proteins in the development of human autoimmune diseases such as juvenile chronic arthritis.

引用

页码：S25 / S28

页数：4

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[41] Potential role of heat-shock proteins in giant cell tumors [J].

Chen, J. T. ;

Younusi, A. ;

Cao, L. ;

Tian, Z. ;

Zhou, Y. J. ;

Song, X. H. .

GENETICS AND MOLECULAR RESEARCH, 2015, 14 (04) :19144-19154

[42] Implications of antibodies to heat-shock proteins in ischemic heart disease [J].

Hoymans, Vicky Y. ;

Bosmans, Johan M. ;

Van Herck, Paul L. ;

Ieven, Margareta M. ;

Vrints, Christiaan J. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2008, 123 (03) :277-282

[43] SYNTHESIS OF HEAT-SHOCK PROTEINS IN LEAVES OF ARABIDOPSIS-THALIANA [J].

KLYUEVA, NY ;

SAMOKHVALOV, IM .

SOVIET PLANT PHYSIOLOGY, 1990, 37 (04) :564-571

[44] PHYLOGENY OF THE ALPHA-CRYSTALLIN-RELATED HEAT-SHOCK PROTEINS [J].

PLESOFSKYVIG, N ;

VIG, J ;

BRAMBL, R .

JOURNAL OF MOLECULAR EVOLUTION, 1992, 35 (06) :537-545

[45] Immunological aspects of heat-shock proteins -: the optimum stress of life [J].

Prohászka, Z ;

Füst, G .

MOLECULAR IMMUNOLOGY, 2004, 41 (01) :29-44

[46] Oral microbial heat-shock proteins and their potential contributions to infections [J].

Goulhen, F ;

Grenier, D ;

Mayrand, D .

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE, 2003, 14 (06) :399-412

[47] Effect of geldanamycin on expression of signal proteins and heat-shock proteins in normal mouse lymphocytes [J].

Novoselova T.V. ;

Cherenkov D.A. ;

Khrenov M.O. ;

Glushkova O.V. ;

Lunin S.M. ;

Novoselova E.G. ;

Fesenko E.E. .

Cell and Tissue Biology, 2008, 2 (4) :366-372

[48] Heat shock proteins and their immunomodulatory role in inflammatory arthritis [J].

Spierings, Julia ;

van Eden, Willem .

RHEUMATOLOGY, 2017, 56 (02) :198-208

[49] Bioresonance therapy of rheumatoid arthritis and heat shock proteins [J].

Islamov, BI ;

Funtikov, VA ;

Bobrovskii, RV ;

Gotovskii, YV .

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1999, 128 (11) :1112-1115

[50] Heat shock proteins in rheumatoid arthritis: friend or foe? [J].

Tukaj, Stefan ;

Lipinska, Barbara .

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, 2011, 65 :427-436

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