MALIGNANT GERM-CELL TUMORS IN 2 SIBLINGS

被引:6
作者
BLAKE, KI [1 ]
GERRARD, MP [1 ]
机构
[1] CHILDRENS HOSP,DEPT PAEDIAT ONCOL,WESTERN BANK,SHEFFIELD S10 2TH,S YORKSHIRE,ENGLAND
来源
MEDICAL AND PEDIATRIC ONCOLOGY | 1993年 / 21卷 / 04期
关键词
FAMILIAL; GERM CELL TUMOR; OVARIAN; MALIGNANT;
D O I
10.1002/mpo.2950210413
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Familial germ cell tumours are well recognised in kinship with gonadal dysgenesis, but their occurrence in siblings with normal chromosomes is rare. We report two sisters who presented within a 4 month period with malignant ovarian germ cell tumours; one a dysgerminoma and the other a mixed tumour with marked choriocarcinomatous elements. Both children had a normal female constitutional karyotype and normal phenotype.
引用
收藏
页码:299 / 300
页数:2
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