MALIGNANT GERM-CELL TUMORS IN 2 SIBLINGS

被引：6

作者：

BLAKE, KI ^{[1
]}

GERRARD, MP ^{[1
]}

机构：

[1] CHILDRENS HOSP,DEPT PAEDIAT ONCOL,WESTERN BANK,SHEFFIELD S10 2TH,S YORKSHIRE,ENGLAND

来源：

MEDICAL AND PEDIATRIC ONCOLOGY | 1993年 / 21卷 / 04期

关键词：

FAMILIAL; GERM CELL TUMOR; OVARIAN; MALIGNANT;

D O I：

10.1002/mpo.2950210413

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Familial germ cell tumours are well recognised in kinship with gonadal dysgenesis, but their occurrence in siblings with normal chromosomes is rare. We report two sisters who presented within a 4 month period with malignant ovarian germ cell tumours; one a dysgerminoma and the other a mixed tumour with marked choriocarcinomatous elements. Both children had a normal female constitutional karyotype and normal phenotype.

引用

页码：299 / 300

页数：2

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