Retrotracheal Parathyroid Adenoma Presenting with Mandibular Giant Cell Granuloma

For the past two decades, primary hyperparathyroidism generally has been diagnosed at an asymptomatic stage because of routine biochemical screening. Bone involvement and dental changes are late manifestations of primary hyperparathyroidism, and brown tumors are seen rarely. We present here a case who admitted to the dentistry clinic with left mandibular swelling diagnosed on pathologic examination as giant cell granuloma. Further investigation revealed brown tumors localized to the mandible and was secondary to primary hyperparathyroidism. Primary hyperparathyroidism can present in a variety of ways and should be included in the differential diagnosis of cystic bone lesions, although at present, these lesions are seen rarely.