ANTIDIARRHEIC ACTIVITY OF EUPHORBIA-HIRTA EXTRACT AND ISOLATION OF AN ACTIVE FLAVONOID CONSTITUENT

被引：156

作者：

GALVEZ, J ^{[1
]}

ZARZUELO, A ^{[1
]}

CRESPO, ME ^{[1
]}

LORENTE, MD ^{[1
]}

OCETE, MA ^{[1
]}

JIMENEZ, J ^{[1
]}

机构：

[1] UNIV GRANADA,FAC FARM,DEPT FARMACOL,E-18071 GRANADA,SPAIN

来源：

PLANTA MEDICA | 1993年 / 59卷 / 04期

关键词：

EUPHORBIA-HIRTA; ANTIDIARRHEIC ACTIVITY; QUERCITRIN;

D O I：

10.1055/s-2006-959694

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The antidiarrhoeic activity of the Euphorbia hirta whole plant was investigated. The lyophilized decoction demonstrated antidiarrhoeic activity in experimental models of diarrhoea induced by castor oil, arachidonic acid, and prostaglandin E2. It showed no activity when magnesium sulphate was used to provoke the diarrhoea. The lyophilized decoction delayed small intestinal transit when this was accelerated by castor oil but not in normal conditions. A flavonoid, quercitrin, with antidiarrhoeic activity was isolated from this crude drug.

引用

页码：333 / 336

页数：4

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