Human miRNome profiling in colorectal cancer and liver metastasis development

被引：8

作者：

Perilli, Lisa ^{[1
]}

Pizzini, Silvia ^{[1
]}

Bisognin, Andrea ^{[2
]}

Mandruzzato, Susanna ^{[1
,3
]}

Biasiolo, Marta ^{[2
]}

Facciolli, Arianna ^{[1
]}

Rossi, Elisabetta ^{[1
]}

Esposito, Giovanni ^{[3
]}

Rugge, Massimo ^{[4
]}

Pilati, Pierluigi ^{[5
]}

Mocellin, Simone ^{[5
]}

Nitti, Donato ^{[5
]}

Bortoluzzi, Stefania ^{[2
]}

Zanovello, Paola ^{[1
,3
]}

机构：

[1] Univ Padua, Dept Surg Oncol & Gastroenterol, Oncol & Immunol Sect, Padua, Italy

[2] Univ Padua, Dept Biol, Padua, Italy

[3] IRCCS, IOV, Padua, Italy

[4] Univ Padua, Dept Med DIMED, Surg Pathol & Cytopathol Unit, Padua, Italy

[5] Univ Padua, Dept Surg Oncol & Gastroenterol, Surg Clin, Padua, Italy

来源：

GENOMICS DATA | 2014年 / 2卷

关键词：

microRNA; Microarray; Colorectal cancer; Metastasis;

D O I：

10.1016/j.gdata.2014.06.017

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor and liver metastasis samples. Using this dataset, we describe the interplay of miRNA groups in regulating pathways that are important for tumor development. Here we describe in details the contents and quality controls for the miRNA expression and clinical data associated with the study published by Pizzini and colleagues in the BMC Genomics in 2013 (Pizzini et al., 2013). Data are deposited in GEO database as GSE35834 series. (C) 2014 The Authors. Published by Elsevier Inc.

引用

页码：184 / 188

页数：5

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