CIRCULATING EPIDERMAL GROWTH-FACTOR (EGF) AND INSULIN-LIKE GROWTH-FACTOR-I (IGF-I) IN PATIENTS WITH EPITHELIAL OVARIAN-CARCINOMA

被引：0

作者：

SHAH, NG ^{[1
]}

BHATAVDEKAR, JM ^{[1
]}

DOCTOR, SS ^{[1
]}

SUTHAR, TP ^{[1
]}

BALAR, DB ^{[1
]}

DAVE, RS ^{[1
]}

机构：

[1] GUJARAT CANC SOC,AHMEDABAD 380016,GUJARAT,INDIA

来源：

NEOPLASMA | 1994年 / 41卷 / 05期

关键词：

EGF; IGF-I; EPITHELIAL OVARIAN CARCINOMA; PROGNOSTICATORS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Circulating epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) were estimated in 58 patients with epithelial ovarian cancer and were correlated with clinically and biochemically important prognosticators. IGF-I levels were significantly low in patients as compared to controls. The relation of growth factors with clinically important prognosticators was non-significant. Moreover, the levels of EGF and IGF-I in the ER(+)/PR(+) and ER(-)/PR(-) groups and in the low and high EGFR+ tumors did not differ significantly. Patients with EGF < 1.0 ng/ml had significantly better survival than those with EGF > 1.0 ng/ml.

引用

页码：241 / 243

页数：3

共 13 条

[1]

BAUKNECHT T, 1989, MED ONCOL TUMOR PHAR, V6, P121

[2] CLINICAL-SIGNIFICANCE OF ONCOGENES AND GROWTH-FACTORS IN OVARIAN CARCINOMAS [J].