MODIFICATION OF TESTICULAR STEROID METABOLISM IN RAT DURING GONADOTROPIN ADMINISTRATION

被引:5
作者
LACROIX, E [1 ]
EECHAUTE, W [1 ]
LEUSEN, I [1 ]
机构
[1] STATE UNIV GHENT, NORMAL & PATHOL PHYSIOL LAB, B-9000 GHENT, BELGIUM
来源
ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE | 1976年 / 84卷 / 05期
关键词
D O I
10.3109/13813457609069453
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The administration of human chorionic gonadotropins to adult rats stimulates the formation of testosterone, 7.alpha.-hydroxy-testosterone and 5.alpha.-androstanediol in incubated testes. When the gonadotropins are injected for several days, the testosterone formation is maintained at a high level; however, the transformation to 7.alpha.-hydroxy-testosterone decreases progressively to subcontrol levels, while 5.alpha.-androstanediol is produced in greater amounts.
引用
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页码:911 / 914
页数:4
相关论文
共 2 条
[1]   INFLUENCE OF AGE ON FORMATION OF 5-ALPHA-ANDROSTANEDIOL AND 7-ALPHA-HYDROXY-TESTOSTERONE BY INCUBATED RAT TESTES [J].
LACROIX, E ;
EECHAUTE, W ;
LEUSEN, I .
STEROIDS, 1975, 25 (05) :649-661
[2]  
LACROIX E, 1974, ANN ENDOCRINOL-PARIS, V35, P683