PURIFICATION AND CHARACTERIZATION OF A NEW HEAT-STABLE ENTEROTOXIN PRODUCED BY VIBRIO-CHOLERAE NON-01 SEROGROUP HAKATA

被引：25
作者：
ARITA, M
HONDA, T
MIWATANI, T
OHMORI, K
TAKAO, T
SHIMONISHI, Y
机构：
[1] RES INST MICROBIAL DIS, 3-1 YAMADAOKA, SUITA, OSAKA 565, JAPAN
[2] OSAKA UNIV, INST PROT RES, SUITA, OSAKA 565, JAPAN
来源：
INFECTION AND IMMUNITY | 1991年 / 59卷 / 06期
关键词：
D O I：
10.1128/IAI.59.6.2186-2188.1991
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The possible production of a heat-stable enterotoxin (Vc-H-ST) by Vibrio cholerae non-O1 serogroup Hakata was investigated, and the purified Vc-H-ST was characterized. It has a unique amino acid sequence, LIDCCEICCNPACFGCLN. This sequence is quite similar to that of the heat-stable enterotoxin (NAG-ST) produced by V. cholerae non-O1 except for one amino acid (leucine) residue excess at the N terminus. Other characteristics, including biological activity, are compatible with those of NAG-ST.
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页码：2186 / 2188
页数：3
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