THE AQUAPORIN FAMILY OF MEMBRANE WATER CHANNELS

被引：49

作者：

ENGEL, A ^{[1
]}

WALZ, T ^{[1
]}

AGRE, P ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV, SCH MED, DEPT BIOL CHEM & MED, BALTIMORE, MD 20205 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(94)90217-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rapid movement of water across the plasma membranes of certain cells has been a long-standing puzzle to membrane biophysicists and physiologists; the discovery of the red cell channel-forming integral protein has provided a molecular solution to this puzzle. The identification-of this protein has led to the recognition of a family of related water-selective channels, the aquaporins, that are found in animals, plants and microbial organisms. In order to provide insight into the remarkable but simple function of these membrane proteins, their structures are being elucidated.

引用

页码：545 / 553

页数：9

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