GLUCAGON STIMULATES ADENYLATE-CYCLASE THROUGH GR2 GLUCAGON RECEPTORS - A PROCESS WHICH CAN BE ATTENUATED BY GLUCAGON STIMULATING INOSITOL PHOSPHOLIPID-METABOLISM THROUGH GR1 GLUCAGON RECEPTORS

被引：20
作者：
HOUSLAY, MD
WAKELAM, MJO
MURPHY, GJ
GAWLER, DJ
PYNE, NJ
机构：
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 1987年 / 15卷 / 01期
关键词：
D O I：
10.1042/bst0150021
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：21 / 24
页数：4
相关论文
共 17 条
[1]  
BIRNBAUM MJ, 1977, J BIOL CHEM, V252, P528
[2]   ANGIOTENSIN-II INHIBITS THE ACCUMULATION OF CYCLIC-AMP PRODUCED BY GLUCAGON BUT NOT ITS METABOLIC EFFECTS [J].
CARDENASTANUS, RJ ;
HUERTABAHENA, J ;
GARCIASAINZ, JA .
FEBS LETTERS, 1982, 143 (01) :1-4
[3]   METABOLIC EFFECTS AND CYCLIC-AMP LEVELS PRODUCED BY GLUCAGON, (1-N-ALPHA-TRINITROPHENYLHISTIDINE,12-HOMOARGININE)GLUCAGON AND FORSKOLIN IN ISOLATED RAT HEPATOCYTES [J].
CORVERA, S ;
HUERTABAHENA, J ;
PELTON, JT ;
HRUBY, VJ ;
TRIVEDI, D ;
GARCIASAINZ, JA .
BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 804 (04) :434-441
[4]   CHALLENGE OF HEPATOCYTES BY GLUCAGON TRIGGERS A RAPID MODULATION OF ADENYLATE-CYCLASE ACTIVITY IN ISOLATED MEMBRANES [J].
HEYWORTH, CM ;
HOUSLAY, MD .
BIOCHEMICAL JOURNAL, 1983, 214 (01) :93-98
[5]   ISLET-ACTIVATING PROTEIN BLOCKS GLUCAGON DESENSITIZATION IN INTACT HEPATOCYTES [J].
HEYWORTH, CM ;
HANSKI, E ;
HOUSLAY, MD .
BIOCHEMICAL JOURNAL, 1984, 222 (01) :189-194
[6]   INSULIN EXERTS ACTIONS THROUGH A DISTINCT SPECIES OF GUANINE-NUCLEOTIDE REGULATORY PROTEIN - INHIBITION OF ADENYLATE-CYCLASE [J].
HEYWORTH, CM ;
HOUSLAY, MD .
BIOCHEMICAL JOURNAL, 1983, 214 (02) :547-552
[7]   THE PHORBOL ESTER, TPA INHIBITS GLUCAGON-STIMULATED ADENYLATE-CYCLASE ACTIVITY [J].
HEYWORTH, CM ;
WHETTON, AD ;
KINSELLA, AR ;
HOUSLAY, MD .
FEBS LETTERS, 1984, 170 (01) :38-42
[8]   THE PHORBOL ESTER TPA PREVENTS THE EXPRESSION OF BOTH GLUCAGON DESENSITIZATION AND THE GLUCAGON-MEDIATED BLOCK OF INSULIN STIMULATION OF THE PERIPHERAL PLASMA-MEMBRANE CYCLIC-AMP PHOSPHODIESTERASE IN RAT HEPATOCYTES [J].
HEYWORTH, CM ;
WILSON, SP ;
GAWLER, DJ ;
HOUSLAY, MD .
FEBS LETTERS, 1985, 187 (02) :196-200
[9]   INSULIN AND GLUCAGON REGULATE THE ACTIVATION OF 2 DISTINCT MEMBRANE-BOUND CYCLIC-AMP PHOSPHODIESTERASES IN HEPATOCYTES [J].
HEYWORTH, CM ;
WALLACE, AV ;
HOUSLAY, MD .
BIOCHEMICAL JOURNAL, 1983, 214 (01) :99-110
[10]   A FAMILY OF GUANINE-NUCLEOTIDE REGULATORY PROTEINS [J].
HOUSLAY, MD .
TRENDS IN BIOCHEMICAL SCIENCES, 1984, 9 (02) :39-40
12