HEPATIC-FAILURE IN A CASE OF MULTIPLE MYELOMA-ASSOCIATED AMYLOIDOSIS (KAPPA-AL)

被引:34
作者
YAMAMOTO, T
MAEDA, N
KAWASAKI, H
机构
[1] Second Department of Internal Medicine, Tottori University Faculty of Medicine, Yonago
[2] Department of Gastroenterology, Hamada National Hospital, Hamada
关键词
HEPATIC FAILURE; MULTIPLE MYELOMA; AMYLOIDOSIS; IGG-KAPPA;
D O I
10.1007/BF02347517
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
We report a case of kappa-AL amyloidosis which rapidly developed hepatic failure in a 79-year-old Japanese female who was admitted to our hospital because of abdominal distension and loss of appetite. Laboratory examination revealed a marked deterioration of liver function with cholestasis and monoclonal gammapathy. At the time that the diagnosis of IgG-kappa type multiple myeloma was made, jaundice was advanced, with continuous gastrointestinal bleeding. The patient died of hepatic failure 2 weeks after admission. Needle biopsy of the liver revealed a diffuse, massive deposition of amyloid protein.
引用
收藏
页码:393 / 397
页数:5
相关论文
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